A single-copy gene encodes Kex1, a serine endoprotease of Pneumocystis jiroveci.
نویسندگان
چکیده
We have cloned and characterized the kex1 gene of Pneumocystis jiroveci. Unlike the case for Pneumocystis carinii, in which the homologous PRT-1 genes are multicopy, kex1 is a single-copy gene encoding a protein homologous to fungal serine endoproteases, which localize to the Golgi apparatus. Thus, substantial biological differences can be seen among Pneumocystis species.
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عنوان ژورنال:
- Infection and immunity
دوره 71 1 شماره
صفحات -
تاریخ انتشار 2003